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Serious allergic reactions happen in less than 1% of cases but can include throat swelling, severe rash, and breathing difficulty requiring immediate emergency care

However, as Moncrieff and colleagues point out in an attractive systemic review, there is no convincing evidence that depression could be associated with or caused by lower serotonin concentrations or activity [94]

This means it hasn't undergone the rigorous testing required to ensure its safety and efficacy

PMID: 100 HaJHRadhakrishnanRNadhanRGomathinayagamRJayaramanMYanMet al