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65 Taken together, there has been continued progress in the field of large-scale cartilage repair, with multiple approaches now being tested in clinically relevant large animal models

The chemokine CCL2 mediates migration that increased BBB permeability, as shown when HIV-1 infected lymphocytes were added to transwells with astrocytes and BECs (Eugenin et al., 2006)

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The main limitation is absorption