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Ca 2+ -driven cell death of erythrocytes can occur even without activation of caspases

the body synthesizes it and animal-based foods (meat, fish, dairy) provide it

doi: 10.3389/fsufs.2020.00106 Received 20 May 2020 Accepted 16 June 2020 Published 10 July 2020 Volume 4 - 2020 Edited by Everlon Cid Rigobelo, So Paulo State University, Brazil Reviewed by Noemi Carla Baron Cozentino, So Paulo State University, Brazil

5.2 Microbial factors directly modulating -cells: LPS, indoles and BefA SCFAs, particularly butyrate, protect -cells not only by enhancing GLP-1 secretion but also through profound immunomodulatory effects that attenuate islet inflammation