When paired with endotoxin-free peptides , bacteriostatic water helps maintain solution integrity during multi-use laboratory workflows, provided endotoxin-controlled handling and storage protocols are followed
As Novo and Lilly resolve supply constraints, the FDA is beginning the transition away from the temporary flexibility that enabled widespread compounding in the first place
Plain sterile water is not preservative-free bacteriostatic once the vial seal is broken, it is susceptible to microbial contamination and should only be used for single-draw applications
Even low levels of endotoxin contamination can trigger unintended inflammatory signalling in cell-based assays, significantly confounding results
In a further embodiment, the low temperature sterile filtration occurs at a temperature between 0 and 30 C., or between 0 and 20 C., or between 0 and 10 C., or between 10 and 20 C., or between 20 and 30 C