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Principal exogenous antioxidants, namely, diet-derived antioxidants, include -carotene, retinol, vitamin C, vitamin E, and vitamin B6 ( FIGURE 1 Antioxidants can theoretically prevent tumorigenesis, and their cancer-suppressing function has been observed in several mouse tumor models

doi: 10.1001/jama.296.1.87 97 WeiM.ZhengZ.ShiL.JinY.JiL

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The presence of unprotected peptide bonds at both the N- and C-terminal linkages predicts that Norleual should have poor metabolic stability and rapid clearance for the circulation, properties that may limit its clinical utility

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