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Protective effect of glutathione against oxidative stress-induced cytotoxicity in RAW 264.7 macrophages through activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 pathway

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This directly activates the downstream Wnt/-catenin, phosphatidylinositol 3-kinase/protein kinase B/mechanistic target of rapamycin (PI3 K/Akt/mTOR), mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK), and AMP-activated protein kinase (AMPK) signaling pathways, promoting the expression of Cyclin D1 and cellular myelocytomatosis (c-Myc) in fibroid tissue [3133]

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