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10.1016/S0304-3835(01)00383-4 Cleusix V, Lacroix C, Vollenweider S, Duboux M, Le Blay G: Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteria

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Detailed and structured history taking that captures symptom onset, severity, cyclical patterns, and associated features such as gastrointestinal or urinary symptoms has been shown to improve diagnostic suspicion