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This observed beneficial effect could be mediated through a reduction in body mass index (BMI), leptin concentration and body fat percentage (43)

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For example, renal endothelial cells (critical for maintaining microvascular integrity) or mesangial cells may also undergo ferroptosis in response to contrast agents, yet their role in amplifying CIN injury (e.g., via paracrine signaling or microvascular rarefaction) has not been rigorously characterized

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