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It's about choosing the right tool for the specific, often moving-target objective you're trying to achieve

Little J, Higgins JPT, Ioannidis JPA, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J: Strengthening the reporting of genetic association studies (STREGA)--an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement

It roams the cellular environment looking for unstable molecules and heavy metals, latching onto them so they can be safely escorted out of the body

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