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While the copper amounts in standard GHK-Cu doses are small, prolonged daily exposure without breaks allows gradual accumulation

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Storage & Handling: Store unopened vials at controlled room temperature: 20C to 25C (68F to 77F) After first puncture, store under refrigeration: 2C to 8C (36F to 46F) Do not freeze Use aseptic techniques to maintain sterility Discard any unused portion within 28 days of first puncture according to proper laboratory protocols Compliance Notice: This product is sold strictly for research purposes and is not approved for use in humans or animals

doi: 10.1016/j.bone.2016.09.023, 36

Walter et al., 1996