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also reported that aberrant Gln metabolism is closely associated with the malignant phenotype of tumor cells [52]

These data demonstrate that SsCm1 is secreted by S

We investigated the inhibition of glutaminase in CLL cell lines and treatment-nave primary CLL lymphocytes and the consequences for cell growth and survival

In this paradigm, aquaporin 8 silencing, which is specifically expressed in IMM, enhances mitochondrial ROS generation and results in mitochondrial depolarization and cell death ( 2 O 2 at higher rates than complex I from mitochondria ( Peroxynitrite is a potent oxidant that is generated upon the reaction of superoxide with nitric oxide (NO)

Because of its central role in immune protection and cellular health, it is considered an essential component of the immune system