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Arch Toxicol 57:125129 Buchet JP, Lauwerys R (1987) Study of factors influencing the in vivo methylation of inorganic arsenic in rats

Greene CM, Chhabra R, McElvaney NG (2013) Is there a therapeutic role for selenium in alpha-1 antitrypsin deficiency

The fact that cardiomyocyte iron overload is a storage problem and not an infiltrative process indicates that iron can be removed to reverse cardiac iron overload and associated damage (39)

In summary, the findings confirm that ferroptosis is a detrimental and targetable factor in MS

However, the translation from rodent research to human outcomes is not guaranteed, and no large randomized controlled trials in humans have been published