Under oxidative stress and induced by excessive ROS generation, Nrf2 is released from its inhibitor Keap1, allowing its translocation into the nucleus (Kasprzak et al., 2020), where it binds to the antioxidant response element (ARE) present in the DNA sequence of numerous antioxidant enzymes like glutathione-S-transferase, -glutamyl cysteine synthetase (glutamate cysteine ligase), heme oxygenase 1, and paraoxonase-1 inducing their transcription, managing the phase II response to oxidative stress (Kasprzak et al., 2020)
Indulge in the luxurious skincare experience you deserve and embrace the confidence that comes with beautifully illuminated skin
Chemical burns can continue damaging tissue until the causative agent is completely neutralized or removed
If you have unexplained copper metabolism concerns or suspect sensitivity, consult your healthcare provider before considering any copper-containing peptide therapy
It may support a healthy extracellular matrix, which contributes to skin firmness and elasticity