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It sparked a national debate about nicotine and provided one of the first definitions of tobacco harm reduction from an official and highly credible source

Julia Eze, MSN, RN, NP-C, is a board-certified Family Nurse Practitioner based in Atlanta, Georgia

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Large studies have found varenicline to be effective and well tolerated: compared to those who received placebo, smokers who received varenicline while trying to quit were more than two and a half times more likely to be cigarette-free one year after entering the trial