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Distribution of the ghrelin receptor In rat tissues, the ghrelin receptor is abundantly expressed in the hypothalamic arcuate nucleus, a key center for feeding regulation ( Although the ghrelin receptor is predominantly expressed in the central nervous system, a broad expression pattern of the gene encoding the ghrelin receptor is observed in various peripheral tissues, including the thyroid, pancreas, spleen, myocardium, adrenal gland, testis, ovary, stomach, and intestinal neurons ( In human tissues, the ghrelin receptor mRNA has been detected in the normal anterior pituitary gland, pituitary adenoma, hypothalamus, and hippocampus

Form and function in cyclic peptide natural products: a pharmacokinetic perspective

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10.1002/jcp.24114 J

Kong, C