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A pack-year is generally calculated by multiplying the number of cigarette packs smoked per day by the number of years a person smoked

The elimination of combustion in smoke-free alternatives also come with other benefits IQOS produces no ash, and does not produce smoke

Further investigation is required to identify beneficial components in coffee, including caffeine and phenolic acids, to develop preventive medication for stroke

There remains an unmet need and lack of a standardized approach to comprehensively evaluate these variables, especially when considering the rapidly changing tobacco product market

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