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The study included a 26-week treatment period including up to six weeks of dose escalation, followed by a 6-week post-treatment follow-up, extending to week 32

After withdrawal of a blood sample, the mice were allowed to recover for at least 1 day and the average running wheel activity over the next two days was taken as baseline value

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Nevertheless, these can substantiate BPC 157 pleiotropic beneficial effects [124,125] based on the wide antagonizing potential of BPC 157 therapy on various NO-system disturbances (L-NAME-related, L-arginine-related [124,125], NO-donors-related (report in preparation))

Compound 102 passed the PAINS (pan assay interference compounds) remover, which filters out compounds that appear as frequent hitters (promiscuous compounds) in many biochemical high throughput screens