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The schematic illustrates the sequential phases of wound healing and the interplay between key cellular actors (neutrophils, macrophages, fibroblasts, keratinocytes, endothelial cells) and cytokines (e.g., TNF-, IL-6, TGF-, IL-10)

Additionally, a series of genes related to osteogenic differentiation ability were highly expressed in these cells during the process of osteogenic induction, including alkaline phosphatase ( Alp ), osteopontin ( Opn ), osterix ( Osx ), bone morphogenetic protein 2 ( Bmp2 ), runt-related transcription factor 2 ( Runx2 ) (Supplementary Fig

GH itself is actually lipolytic, meaning it promotes fat breakdown

22 , e13115 (2020)

This process ensures that hormone therapies are used appropriately and safely under a doctor's care