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It does this by amplifying Brain-Derived Neurotrophic Factor (BDNF) a natural protein often called Miracle-Gro for the brain. BDNF encourages the growth of new synapses and dendrites, the communication points that connect one neuron to another

A systematic review of 35 prospective cohort studies assessing the association between vitamin B 12 status and cognitive deterioration in older individuals with or without dementia at baseline did not support a relationship between serum vitamin B 12 concentrations and cognitive decline, dementia, or Alzheimers disease (79)

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Some protocols combine both methods