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Indeed, it is known that hydrochlorothiazide can target several ion transporters and enzymes including SLC4A8 , a Na + -dependent Cl /HCO 3 exchanger (NDCBE), SLC26A4 , a Na + -independent Cl /HCO 3 exchanger (Pendrin) and carbonic anhydrases (Pickkers et al., 1999
Polymorphisms in the OPG/RANK/RANKL axis might also be involved in cardiac iron overload (94)
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In isolated myocytes exposed to graded ischemia, Ganetkevich et al