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The D-2HG enantiomer is produced downstream of mutant isocitrate dehydrogenase enzymes in glioma and acute myelogenous leukaemia, and the L-2HG enantiomer is produced under hypoxia

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Clinical studies also support the anti-inflammatory benefits of omega-3

Further Reading For additional peer-reviewed research, see: NNMT inhibitor preclinical study by Neelakantan et al

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