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doi: 10.1016/j.ccell.2022.01.001 85 ZhangAXuYXuHRenJMengTNiYet al

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Although symptomatic therapies like Levodopa and Deep Brain Stimulation (DBS) offer short-term relief, they fail to alter disease progression or address the wide array of nonmotor symptoms and comorbidities

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One of the main causes of weight gain is an active lifestyle combined with age

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In some cases, the dementia and other neurologic symptoms caused by vitamin B 12 deficiency can be reversed by vitamin treatment (42), but reversibility seems to be dependent upon the duration of the associated neurologic complications (41)

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