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Storage conditions that shorten unopened shelf life: heat (extended exposure above 25C), freezing and re-thawing (can crack the stopper seal), direct sunlight (degrades benzyl alcohol), and humid environments (can degrade label readability and obscure exp date)
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It could point to several things: A different cause: your fatigue might stem from thyroid problems, iron deficiency, or sleep apnea rather than B12
Weill Cornell Medicine
