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Also, several pathogenic mechanisms linked to ALS involve redox-sensitive proteins, including protein disulfide isomerase (PDI), thioredoxin, and glutathione (GSH), and recent evidence highlights their importance in neurodegeneration

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Epub 2017 Apr 13

Beyond actin sequestration, T4 has been reported to promote angiogenesis, endothelial cell migration, and keratinocyte movement, and to exert anti-inflammatory effects

As such, we believe that there is a need for more detailed studies outlining the diverse biological functions of GST, in order to assist drug discovery and unlock more exciting possibilities in the realm of tumor treatments