glutathione and cancer stem cell responsive nanomedicine leverages tumor redox imbalance for targeted theranostics | Discover Oncology Key role of the cystine/glutamate

A multitude of studies shows that many people are unable to absorb or store sufficient amounts of vitamin B12

Any overproduction of these ROS can be neutralised by glutathione(GSH)

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

2g) Notch signaling is also critical for pancreas development and endocrine specification

Upon oxidation, bilirubin is converted into various forms of bilirubin oxidation metabolites (BOMs), comprising at least seven hydrophilic metabolites that are promptly excreted into urine because of their hydrophilic nature (132)