These agents proved to be effective in PsA as well and, despite increasing evidence of the differences between PsA and RA, they have become an important part of the treatment algorithm for both diseases
[34] Julius, M., Lang, C.A., Gleiberman, L., Harburg, E., Difranceisco, W
PRECAUTIONS OF USE Data from clinical studies and extensive use in clinical practice and as over-the-counter supplementation have demonstrated that oral NAC is generally well-tolerated and safe, even at high doses [9, 12]
doi: 10.1186/s13023-021-01847-9
It has been observed to upregulate genes associated with tissue repair and antioxidant defense while downregulating genes linked to inflammation and fibrosis