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Nanoparticles can be used to encapsulate the viral antigen into the nanoparticle core (e.g., mRNA lipid nanoparticles), or they can present the antigen as protein on the surface of the nanoparticles (e.g., virus-like particles, protein nanoparticles)

Pain behaviors in these rats and the time course of mechanical hyperalgesia are similar to patients pain reports in the postoperative period [12]