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It is not possible to predict if such an activity could be effective in the vagina, since, to our knowledge, the vaginal concentration of H2O2 in women with H2O2-producing lactobacilli has never been determined

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372,373 Moreover, the -face of Cu I -coordinated His ligand interacts with residues in the second coordination shell including nearly invariant Tyr and Glu residues that are energetically linked to Cu I -mediated allosteric inhibition of DNA binding, suggesting a path for allosteric connectivity

The voxel was positioned to avoid the skull and, to the extent possible, the left lateral ventricle (Figure 4)

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