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FIGURE 2 6 Conclusion and future perspectives Therapeutic approaches to address oxidative stress typically involve upregulating antioxidant signals such as NRF2, administering exogenous antioxidants, supplementing trace elements or nutrients, and implementing environmental interventions (Forman and Zhang, 2021)

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Mazurowska, L

Mothballs contain naphthalene, a polycyclic aromatic hydrocarbon, which enhances the production of ROS, leading to oxidative stress in G6PD-deficient RBCs ( In cases of breastmilk transmitted favism and naphthalene contact or vapor inhalation, the G6PD-deficient infants with acute hemolysis showed the presence of Heinz bodies in their blood films ( The other triggers of acute hemolytic anemia include certain medications such as anti-malarials, and to a lesser extent, bacterial or viral infection