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The TRIUMPH-1 trial enrolled adults with a BMI of 30 or above, or a BMI of at least 27 plus a weight-related health condition

These insights suggest that interventions aimed at restoring gut microbiota balancethrough dietary modifications, probiotics, fecal microbiota transplantation, etc.may offer novel therapeutic strategies to alleviate the debilitating symptoms of this complex condition [1, 8]

This article aims to provide a comprehensive answer by examining its mechanism of action, experimental data, influencing factors, and typical timelines