TGF-, PDGF, EGF, and FGF have been shown to stimulate infiltration of inflammatory cells into the wound space.24 These growth factors induce proliferation of keratinocytes and fibroblasts, lead to new formation of capillaries in the granulation tissue, and modulate extracellular matrix deposition and reconstitution of the injured area.25 The topical application of growth factors was successful in accelerating healing of full-thickness wound in normal mice.8,9 The pentadecapeptide body protective compound (BPC)-157 ( Mr 1419), with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, a 15-amino acid fragment of the BPC peptide in gastric juice, is thought to be essential for BPCs activity and has been fully characterized and investigated
There are no dosing protocols standardised during the approval process
Note: Doses above 1.0 mL (100 units) require a 3 mL syringe with an appropriate subcutaneous needle (e.g., 2527G, inch) rather than a standard U100 insulin syringe
For many people, this results in more noticeable benefits compared to pills or sublingual options
Tetrahydrofolic acid, methyltetrahydrofolate, and other folic acid congeners are essential for the maintenance of normal erythropoiesis and are also required cofactors for the synthesis of purine and thymidylate nucleic acids
