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This particular form represents the most reduced and chemically reactive state of cobalamin, rendering it highly receptive to binding a methyl group from a form of vitamin B9 called 5-methyltetrahydrofolate, the product of methylenetetrahydrofolate reductase (MTHFR), to generate methylcobalamin (MeCbl)

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Epithalon and Geroprotective Properties This study (13) was conducted on 266 elderly subjects (over the age of 60 years) throughout 6 to 8 years, where some subjects were presented with peptide-bioregulator Thymalin, others with Epithalon, and the rest with the combination of the two