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To this end, a randomized, double-blinded, placebo-controlled trial found that topical application of a 0.1% amla branch gel for 84 days significantly improved skin hydration, elasticity, tone, and reduced wrinkles without irritation

Post-surgical recovery affecting multiple tissue types, chronic widespread inflammation, and patients whose primary complaint is global stiffness and reduced range of motion that has not improved with localized treatment all fit the TB-500 indication

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Additionally, the experiments were conducted in accordance with the Animal Research: Reporting of in Vivo Experiments (ARRIVE) guidelines [76] for the care and use of research animals