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The clinical evidence in humans is accumulating but not yet definitive

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For example, in this case, a Maryland man was criminally prosecuted for selling bodybuilding peptides with research/laboratory use only claims, which the government explained were used as a ruse to avoid FDA scrutiny. This case saw the same result, with the government explaining that the defendants employed the bogus research chemicals disclaimer to conceal that they and others were distributing misbranded drugs and unapproved new drugs for use by their customers. Ultimately, GLP-1s are a relatively new phenomenon presenting many novel legal issues for FDA and stakeholders

it may simply be an adherence issue that is responsible for a lack of response