When your vitamin B12 level is low, your level of MMA rises
The peptide sequence (glycine-histidine-lysine) chelates copper ions in a way that allows controlled cellular uptake without the oxidative damage that free copper can cause
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However, taking it at night is also an option, as the body undergoes significant cellular repair while you sleep
Sasaki K, Kantarjian HM, Jabbour E, Quintas-Cardama A, Pierce S, Borthakur G , Kadia TM, Pemmaraju N, Ferrajoli A, O'Brien S, Cortes JE