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The active region of TB-500 (the LKKTETQ sequence) binds G-actin monomers, preventing their polymerization into filamentous F-actin

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Researchers should note that more investigation is needed to fully comprehend this peptides mechanisms and effects

Given its current priorities, the Company decided to put on hold the development of M1Pram and will continue to evaluate the path forward for M1Pram as the type 1 diabetes treatment landscape continues to evolve