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Antibiotic survival assays in human PBMC-derived macrophages Human PBMCs were isolated from fresh blood samples using Ficoll-Paque density gradient centrifugation, as described for neutrophil isolation

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A pharmacokinetics study published in Frontiers in Pharmacology found an average intravenous elimination half-life (t1/2) of 15.2 minutes in rats, with the intramuscular peak plasma concentration reached at 3 minutes post-injection