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Electronic databases searched included PubMed, Scopus, Web of Science, ScienceDirect, Google Scholar, and patent repositories such as Google Patents, USPTO, CNIPA, and KIPO
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Finally, we repeated the cellcell interaction and co-expression network analyses under the China/Asia-based control framework
However, adverse effects may limit the treatment potential, e.g., glitazones are associated with phenotypical weight gain [136] and obeticholic acid induced pruritus and elevated LDL-C [137], the latter a potential concern in patients already at risk for cardiovascular disease