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Nonylphenol affects myocardial contractility and L-type Ca 2 + channel currents in a non-monotonic manner via G protein-coupled receptor 30

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This process is potentially dangerous to cells, as peroxidation of mitochondrial phospholipids may affect the integrity of permeability transition pores (PTPs) and disaggregate complexes I and III of the respiratory chain, thereby enhancing electron leakage within the mitochondrial intermembrane space 5,6

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