zhou 2011 glutathione s-transferase activator furanone The Multifaceted Role of S-Transferases in Health and Disease Insights into the toxicity, biochemical

This anti-fibrotic property has generated interest in pulmonary research, where researchers are exploring its potential in lung tissue preservation models

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Further, we included ascorbic acid in our formulation, as it is essential for human health, is present in abundance in the Brassicaceae family, and has been definitively identified as a required cofactor for Myr activity based on enzymology and X-ray crystallography in a reaction that is independent of its reducing capacity 35,61

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15 Being a powerful antioxidant, glutathione plays a critical role in several metabolic pathways: DNA and protein synthesis, amino acid transport, enzyme activation, immune system function, scavenging free radicals eg hydrogen peroxide, cofactor in Phase I cytochrome P450 enzyme-mediated detoxification, amino acid translocation across cell membranes, detoxification of xenobiotics, maintenance of sulfhydryl groups of proteins, mitochondrial function and maintenance of mitochondrial DNA, catalysis of exchange reactions and many more