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Attractive targets include members of the LOX family, namely LOX and LOX-like 2 (LOXL2), which mediate collagen and/or elastin crosslinking [97, 98], thereby contributing to ECM remodeling in the tumor microenvironment

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Other rare side effects might include liver problems (indicated by yellowing of the skin or eyes), changes in blood cell counts, and severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis