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However, free radicals generated as a result of metabolic events can accumulate in the body and lead to the deterioration of the egg or sperm

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Myocardial remodelling characterized by fibrosis and hypertrophy, impaired microcirculation, abnormal protein function caused by advanced glycation end products, changes in myocardial metabolism and abnormal mitochondrial function have been noted as associated factors of diabetic cardiomyopathy [14]

A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer