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Tobacco Health Risks The tobacco component introduces several health concerns: Nicotine addiction develops quickly, even with occasional spliff use Respiratory irritation tobacco smoke is more irritating than cannabis smoke alone Cardiovascular effects nicotine increases heart rate and blood pressure Cancer risk tobacco contains numerous carcinogenic compounds Reduced lung function combination smoking may compound respiratory impacts Medical Patient Considerations Medical cannabis patients should carefully weigh spliff use against their treatment goals

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Firstly, the observed potential dose-response relationship between smoking and HTN reinforces the necessity of routine smoking status and intensity assessment in primary care, especially for individuals at risk for or diagnosed with HTN

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