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Six months of monthly radiofrequency treatments with topical serum application produced essentially no side effects, suggesting this approach is well-suited for long-term maintenance therapy

It was suggested that neurotrophin mimetics could stabilize preformed dimers, hence, encourage the receptor activation, considering such a mode of natural ligands action

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If peptides are reconstituted into a solution, they must also be stored at 4C but used within a few days to a week, depending on their specific stability in solution

However, the lack of human safety data, economic disincentives, and doping controversies underscore the challenges ahead