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While corrective lenses continue to dominate revenue generation, surgical procedures and emerging drug therapies are expected to create significant opportunities, particularly in rapidly developing Asia-Pacific markets

Extensive research has been conducted on the decrease in melatonin levels that occurs during both normal ageing and pathological ageing processes in the pineal gland, the brain, and numerous other tissues outside of the pineal gland, as well as in bodily fluids such as cerebrospinal fluid, plasma, saliva, and urine (Wu and Swaab 2005

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However, there is considerable individual variation, and many patients notice little change initially

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