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As regards the pathogenic mechanisms, the occurrence of an oxidant stress (resulting from an impaired homocysteine metabolism, which modifies the redox status of extra- and intracellular thiols and thus alters the intracellular redox potential) might play a central role in moderate hyperhomocysteinemia-mediated vascular disorders

Results: Data on 26829 strokes were analysed

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Ulteriorly, the mechanisms of PACS involve viral infection-induced inflammatory and immune responses (Ruf, 2024)

Although the results suggest that KD exacerbates biotin deficiency in mice, human clinical studies are needed to confirm these observations (249)