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Another example is CGA-N12, a synthetic antimicrobial peptide that exerts potent antifungal effects against Candida albicans by inducing reactive oxygen species (ROS) accumulation and collapsing the mitochondrial membrane potential, ultimately triggering apoptosis (Li et al., 2018)

This fundamental methodological distinction remains neglected in a significant fraction of published literature

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Thus, the combined administration of hepsin with NAC optimized the therapeutic outcome, enhancing effectiveness beyond what was achievable with NAC alone

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