40 Despite NBDHEXs promising anticancer activity, consideration should be given to the relatively low GST-target selectivity and poor water-solubility
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Further investigations into baicaleins therapeutic potential, especially using higher-order species, would help facilitate its clinical translation for TBI management
In fact, although more studies are required to increase the selectivity of these anticancer ROS-related drugs, the common mechanisms elicited by oncogenes to promote the adaptation to a large set of stress conditions are being revealed in more depth every day, and in a high percentage, they concern the redox balance