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KPV appears to exert its effects via the peptide transporter PepT1 rather than classical melanocortin receptors

See the red line in the graph below: As BAC slowly rises and is under .055: The drinker experiences mild stimulating effects such as increased heart rate, increased energy, self-confidence, sociability, and a feeling of wellbeing or "euphoria." This is the Buzz Zone

A previous study showed that the binding of antiestrogens to ER and particularly to ER can induce the expression of the antioxidant NQO1 74