Epigenetic and Cellular Reprogramming: By blocking NNMT-mediated methylation of nicotinamide, preserves NAD salvage pathway activity, increases SIRT-1 signaling, reduces histone deacetylation, and promotes metabolic reprogramming toward oxidative phosphorylation and glycolysis balance, supporting tissue repair and energy homeostasis 1-4
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In 2015, 32 white rabbits were divided into four groups of eight, and each group was given a placebo, AOD 9604, hyaluronic acid, or a combination of AOD 9604 and hyaluronic acid for 4 to 7 weeks
Unlike full hGH, it does not raise IGF-1 levels or impact blood sugar, making it a more targeted option for metabolic support
Fat Breakdown (Lipolysis) AOD-9604 promotes the breakdown of stored triglycerides into free fatty acids. This effect has been observed in adipose tissue from both lean and obese models